Capsular Typing Method for Streptococcus agalactiae Using Whole-Genome Sequence Data.

نویسندگان

  • Anna E Sheppard
  • Alison Vaughan
  • Nicola Jones
  • Paul Turner
  • Claudia Turner
  • Androulla Efstratiou
  • Darshana Patel
  • A Sarah Walker
  • James A Berkley
  • Derrick W Crook
  • Anna C Seale
چکیده

Group B streptococcus (GBS) capsular serotypes are major determinants of virulence and affect potential vaccine coverage. Here we report a whole-genome-sequencing-based method for GBS serotype assignment. This method shows strong agreement (kappa of 0.92) with conventional methods and increased serotype assignment (100%) to all 10 capsular types.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 54 5  شماره 

صفحات  -

تاریخ انتشار 2016